In the glitzy entertainment capital of Mumbai as dusk descends, actress Sana Azim (Kangana Ranaut) slits her wrists in a hotel room, in an attempt to kill herself. When this news reaches film-maker Aditya Garewal (Shiney Ahuja), he is devastated. Aditya has been searching for Sana, who was intensely involved with him and who had mysteriously disappeared from his life without any explanation, three years ago, only to surface now in what could be the last moments of her life.
As Aditya waits outside the ICU, praying to be reunited with her, he is hurled back into the perfumed days and champagne nights of his memory, when Sana played the role of a lover and mentor to a struggling Aditya.
Everything was perfect, except for an enemy which lurked in the shadows, waiting to destroy their love. When Aditya realizes that the only way he can save Sana from total devastation is to take her away from Bollywood and the vested interests that threaten to destroy her completely, he runs away with Sana putting his career on the line. Those moments lived in the sanctuary of their love are like an oasis in the desert.
Until one day, suddenly, she disappears, leaving him with unanswered questions.
Aditya tries his best to save Sana from her mental illness but fails.